Nattokinase Plus – Cardiovascular & Circulatory Support Supplement

Support healthy circulation and cardiovascular function with Nattokinase Plus, a powerful
enzyme-based supplement designed to promote optimal blood flow and heart health. Derived
from fermented soy (natto), nattokinase is widely used to support fibrin balance and healthy
circulation as part of a heart-healthy lifestyle.
Nattokinase Plus combines nattokinase with complementary nutrients to enhance absorption and
provide comprehensive cardiovascular support.
Key Benefits
 Supports Healthy Circulation – Helps maintain normal blood flow
 Promotes Cardiovascular Health – Supports overall heart and vascular function
 Enzyme-Based Formula – Contains nattokinase derived from fermented soy
 Supports Fibrin Balance – Helps maintain healthy blood viscosity
How It Works
 Nattokinase helps support the body’s natural processes involved in circulation and
vascular health. When used consistently, it supports normal blood flow and complements
a heart-healthy diet and lifestyle.
How Nattokinase May Help in Long COVID
1. Supports Breakdown of Microclots
One of the leading theories about persistent Long COVID symptoms is that tiny resistant blood
microclots form in circulation, potentially impairing oxygen delivery and contributing to:
 fatigue
 shortness of breath
 cognitive fog
 poor stamina
Nattokinase is a fibrinolytic enzyme, meaning it can break down fibrin, a key protein in clots.
Laboratory studies in vitro show that it can reduce numbers and intensity of these microclot
structures under controlled conditions.
By theoretically breaking down microclots and improving circulation, nattokinase could help
with symptoms related to poor blood flow and oxygenation.
2. May Enhance Fibrinolytic Activity

Nattokinase not only directly breaks down fibrin but may also support the body’s own clot-
dissolving systems. This double action has made it of interest for cardiovascular circulation
support in post-viral syndromes.
Improved blood flow might alleviate symptoms like fatigue, dizziness, and cardiovascular
discomfort that some Long COVID sufferers experience.
3. Experimental Spike Protein Degradation (Pre-Clinical)
Some in vitro research suggests nattokinase can degrade SARS-CoV-2 spike protein fragments
under lab conditions. Because persistent viral proteins have been hypothesized to contribute to
ongoing inflammation in Long COVID, this potential action fuels interest in nattokinase.
 The breakdown increased with higher doses and longer exposure
 When nattokinase was added to cells displaying the spike protein on their surface, the
amount of spike protein decreased
 This effect depended on nattokinase’s enzyme activity, when the enzyme was heat-
inactivated or blocked, the effect disappeared
 The concentrations used did not damage the cells, suggesting non-toxic levels in this
laboratory setting
Because the spike protein is essential for the virus to enter cells, these findings suggest that
nattokinase may interfere with viral entry under laboratory conditions.
Important Context and Limitations
It is very important to understand what this study does not show:
 This was not a human clinical trial
 It does not prove that nattokinase prevents or treats COVID-19
 Results were observed only in lab experiments
 Effects in the human body may be very different from what happens in cells in a dish
Disclaimer
 This information is for educational purposes only.
Nattokinase is a dietary supplement and is not intended to diagnose, treat, cure, or
prevent any disease, including COVID-19. Always consult a healthcare professional
before starting any new supplement, particularly if you have medical conditions or take
prescription medications. Nattokinase has blood-thinning effects. It may interact with
anticoagulant medications (like warfarin, aspirin) and increase bleeding risk.
To learn more about Nattokinase Plus, speak with a pharmacist, or purchase this product, please
visit:
 Bluebird Pharmacy: www.bluebirdpharmacy.com
 Our pharmacy team is available to help answer questions and guide you toward
appropriate wellness options.